The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) has expanded its collaboration with the nonprofit MITRE Corporation. The collaboration led to awarding $20 million to NIST to establish two centers to advance the delivery of AI-based technology solutions meant to strengthen U.S. manufacturing and cybersecurity for critical infrastructure.
The AI Economic Security Center for U.S. Manufacturing Productivity and the AI Economic Security Center to Secure U.S. Critical Infrastructure from Cyberthreats will drive the development and adoption of AI-driven tools, or “agents,” in these two national priority areas.
The centers will develop the technology evaluations and advancements that are necessary to effectively protect U.S. dominance in AI innovation, address threats from adversaries’ use of AI, and reduce risks from reliance on insecure AI.
NIST will rely on existing resources to build on its expertise and carry forward recommendations in the White House’s July 2025 America’s AI Action Plan. These are first steps in NIST’s programmatic plan to coordinate innovation-based research efforts for accelerating critical technologies in areas of national priority.
The partnership will leverage MITRE’s long-standing mission to operate federally funded research and development centers. NIST expects the AI centers to enable breakthroughs in applied science and advanced technology and deliver disruptive innovative solutions to tackle the most pressing challenges facing the nation.
This agreement expands NIST’s portfolio of AI-focused programs and builds on the private-public partnerships leveraged by the Center for AI Standards and Innovation (CAISI), which leads evaluations of U.S. and adversary systems and contributes to NIST’s efforts to develop best practices. CAISI has established voluntary agreements with multiple developers of leading-edge or “frontier” AI models to enable collaborative research and voluntary testing of industry models for priority national security capabilities.
In the coming months, NIST plans to announce its award for the AI for Resilient Manufacturing Institute, through the Manufacturing USA program. With up to $70 million in investment over a five-year period from NIST and at least that much in non-federal funding, the institute will bring together expertise in AI, manufacturing and supply chain networks to promote manufacturing resilience.
